Advanced International Journal for Research

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Call for Paper Volume 6, Issue 5 (September-October 2025) Submit your research before last 3 days of October to publish your research paper in the issue of September-October.

Isobaric Ropivacaine 0.5% Vs 0.75% as Spinal Anesthesia

Author(s) Dr. Kiran kumar samantula, Dr. Ravi kiran kaluri, Dr. Beegum Aisha Nazar
Country India
Abstract The study was conducted to compare the clinical differences in the onset, duration of action and complications of intrathecal isobaric Ropivacaine 0.5% [Group A][0.5 GROUP] and intrathecal isobaric Ropivacaine 0.75% [Group B][0.75 GROUP] in lower limb surgeries
Materials and Methods:
60 patients belonging to ASA grade – I and Grade-II of both the sexes (each group 30 patients n=30) were randomly selected for the study. They were randomly allocated to receive either 3 mL glucose-free 0.5% (15 mg) or 0.75% (22.5 mg) isobaric ropivacaine in a non blinded fashion. The subarachnoid puncture was performed with a 25-gauge Quincke- needle at the L 3-L 4 interspace with the patients in the sitting position .The time of onset & duration of sensory and motor block, maximum no of dermatomes blocked and time taken for that, hemodynamic status, time for regression of sensory level to T10 dermatome, time of first request of analgesics and adverse effects were compared in both the groups.

Conclusion:
The subarachnoid injection of glucose-free isobaric Ropivacaine 0.5% and 0.75% solutions results in a variable spread of analgesia, accompanied by a good quality of motor block, Ropivacaine 0.75% produces a better quality of analgesia, longer duration of analgesia than the 0.5% solution.
Keywords isobaric ropivacaine, spinal anesthesia, 0.5% vs 0.75% ropivacaine, lowerlimb surgeries
Field Biology > Medical / Physiology
Published In Volume 6, Issue 5, September-October 2025
Published On 2025-09-04
DOI https://doi.org/10.63363/aijfr.2025.v06i05.1228
Short DOI https://doi.org/g92pk7

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