Advanced International Journal for Research

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Volume 6 Issue 6
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Predictors of Mortality in Elderly Patients Admitted to ICU

Author(s) Alekhya Bandari, Moru Siddeswari, Sourav Jaju, Ghanshyam Yadav, Ega Srinivas
Country India
Abstract Background:
With rapid population ageing, increasing numbers of elderly patients are being admitted to intensive care units (ICUs) in India. Mortality in this group remains high and multifactorial, yet region-specific data identifying prognostic indicators are limited.
Objectives:
To determine clinical, biochemical, and management-related predictors of in-hospital mortality among elderly patients admitted to a tertiary-care ICU.
Methods:
A prospective observational study was conducted in a tertiary hospital ICU between January 2023 and December 2024. Patients aged ≥ 65 years were consecutively enrolled. Data on demographics, comorbidities, admission diagnosis, organ dysfunction, and interventions (mechanical ventilation, vasopressors, renal replacement therapy) were collected.
Results:
Of 210 elderly ICU admissions, 58 (27.6%) died during hospitalization. Nonsurvivors were older (mean 72.4 ± 6.1 vs 69.8 ± 5.8 years, p = 0.02), had higher APACHE II scores (22.1 ± 7.8 vs 15.3 ± 5.4, p < 0.001), greater prevalence of sepsis (60.3% vs 34.8%, p = 0.001), and higher rates of mechanical ventilation (79.3% vs 38.5%, p < 0.001). Multivariate analysis identified APACHE II score > 20 (aOR 3.25, 95% CI 1.85–5.69), septic shock (aOR 2.81, 95% CI 1.52–5.18), mechanical ventilation (aOR 2.66, 95% CI 1.44–4.89), and serum creatinine > 2 mg/dL (aOR 2.42, 95% CI 1.21–4.83) as independent predictors of mortality.
Conclusion:
Severity of illness, sepsis, organ dysfunction, and need for mechanical ventilation are strong determinants of ICU mortality among elderly patients. Early recognition and aggressive management of these risk factors may improve survival outcomes in this vulnerable population.
Keywords Elderly ICU patients • Mortality predictors • APACHE II score • Sepsis • Mechanical ventilation • India
Published In Volume 6, Issue 6, November-December 2025
Published On 2025-11-17
DOI https://doi.org/10.63363/aijfr.2025.v06i06.2114
Short DOI https://doi.org/hbbz7h
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