Advanced International Journal for Research

E-ISSN: 3048-7641     Impact Factor: 9.11

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 6, Issue 6 (November-December 2025) Submit your research before last 3 days of December to publish your research paper in the issue of November-December.

MRSA Trends: A 2 Year Retrospective Observational Study At a Tertiary Care Hospital In Gurugram

Author(s) Dr. Anshu Singhal, Dr. Namita Jaggi
Country India
Abstract OBJECTIVE: MRSA is a major cause of nosocomial and community infections. The growing resistance pattern of S.aureus along with a steady increase in minimum inhibitory concentration of the currently available antibiotics have led to limited drug options. Monitoring of these strains is essential in order to control their spread in the hospital environment and transmission to the community.
DESIGN: It is a 2 year retrospective observational study performed from December 2022 to November 2024 at a tertiary care hospital in Gurugram..
SUBJECTS: All patients registered in the hospital on OPD/IPD basis or requiring ICU level care. Patients with clinically relevant isolate of S.aureus from different clinical specimens would be included in the study.
METHODS: The processing, identification and antibiotic susceptibility would be as per CLSI guidelines.
RESULTS: Out of 7835 clinical specimens, 767 (9.7%) isolates were found to be S.aureus. Majority of them were isolated from skin and soft tissue infections (35.7%)..Out of 767 identified S.aureus, 343 (44.75) isolates were MSSA and the major bulk were 424 (55.2%) MRSA strains. Excellent susceptibility was observed with linezolid and teicoplanin (100%) , however reduced susceptibility was observed for Benzylpenicillin (5%). The prevalence of MRSA in hospital ICU settings showed better efficacy to linezolid, vancomycin and teicoplanin, (100%) compared to fluoroquinolones. However, not much difference was observed in the drug susceptibility pattern in IPD and OPD settings.
CONCLUSION: More than 55% patients with S.aureus infection had MRSA that were resistant to commonly available antibiotics. This calls for strengthening surveillance and good infection control practices in the hospital.
Keywords antibiotic, MRSA, resistance, S.aureus, susceptibility
Field Biology > Genetics / Molecular
Published In Volume 6, Issue 6, November-December 2025
Published On 2025-12-02
DOI https://doi.org/10.63363/aijfr.2025.v06i06.2244
Short DOI https://doi.org/hbdstm

Share this