Advanced International Journal for Research

E-ISSN: 3048-7641   •   Impact Factor: 9.11

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Volume 7 Issue 2
March-April 2026

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In Vitro antibacterial efficacy of aqueous extract of Stachytarpheta indica against Helicobacter pylori and Lactobacillus casei

Author(s) Harshita Singh, Dr. Ritu Thakur Bais
Country India
Abstract The increasing prevalence of antibiotic-resistant pathogens has intensified the search for plant-derived antimicrobial agents. Stachytarpheta indica (L.) Vahl, a traditionally used medicinal herb, possesses bioactive phytochemicals with potential therapeutic applications; however, its antibacterial effects remain insufficiently studied. The present investigation evaluated the in vitro antibacterial efficacy of aqueous leaf extract of S. indica against two clinically relevant bacteria: Helicobacter pylori and Lactobacillus casei. Extract were prepared by infusion (aqueous) while antibacterial activity was assessed using the agar well diffusion method. Results demonstrated solvent- and organism-dependent susceptibility patterns. The aqueous extract showed stronger inhibition against L. casei, likely due to tannin- and glycoside-associated mechanisms. These findings indicate that S. indica possesses broad-spectrum antibacterial potential, with differential activity linked to solvent polarity and bacterial cell structure. Overall, the study supports the medicinal relevance of S. indica and highlights its prospective value in developing plant-based antibacterial formulations.
Keywords Stachytarpheta Indica, Antibacterial Activity, Phyto extracts, Helicobacter Pylori, Agar Well Diffusion Assay
Field Biology > Agriculture / Botany
Published In Volume 7, Issue 2, March-April 2026
Published On 2026-03-13
DOI https://doi.org/10.63363/aijfr.2026.v07i02.3769
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E-ISSN 3048-7641
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