Advanced International Journal for Research

E-ISSN: 3048-7641   •   Impact Factor: 9.11

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Volume 7 Issue 2
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Monkeypox

Author(s) Ms. Aslin Johnsi L, Ms. Brulin Melisha M, Ms. Ida Divya Sherly E, Prof. Dr. Sheeba Chellappan
Country India
Abstract Mpox (formerly known as monkeypox) has re-emerged as a critical global public health priority following the unprecedented multi-country outbreak that began in 2022 and persisted through 2024. Historically confined to Central and West Africa with sporadic zoonotic transmission, mpox transitioned into sustained human-to-human transmission across global networks. This epidemiologic shift revealed new adult clinical phenotypes and exposed critical gaps in antiviral evidence, vaccination equity, infection prevention preparedness, and stigma sensitive care delivery.
Although overall mortality during the 2022–2024 outbreak remained lower than historical Clade I epidemics, the morbidity burden, prolonged symptomatology, complications among immunocompromised populations, and psychosocial sequelae were substantial. Healthcare systems encountered diagnostic uncertainty, evolving infection prevention guidance, limited randomized trial data for therapeutics, and occupational risk concerns for frontline nurses. Adult care environments also faced resource allocation dilemmas and ethical challenges related to isolation and vaccine distribution.
This narrative review critically synthesizes contemporary evidence on mpox in adult care settings, examining epidemiology including incidence rates, etiopathogenesis, pathophysiology, clinical complexity, diagnostic strategies, therapeutic controversies, prognosis, prevention inequities, complications, and the expanding role of nurses in outbreak preparedness and response. Emphasis is placed on translational gaps, ethical challenges in vaccine allocation, and the need for nurse led implementation research. Strengthening interdisciplinary collaboration and nursing scholarship is essential to enhance resilience against future mpox resurgence and other emerging zoonotic threats.
Keywords Mpox, Monkeypox virus, adult nursing, Infection prevention, Tecovirimat, Vaccine equity, public health preparedness
Field Medical / Pharmacy
Published In Volume 7, Issue 2, March-April 2026
Published On 2026-03-09
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E-ISSN 3048-7641
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