Eco-friendly Biosynthesis of Iron Oxide Nanoparticles using Lichen Ramalina fastigiata and its Biological Properties

Author(s)	Dr. Razia Muthusamy, Ms. Kiruthika Senthilkumar
Country	India
Abstract	Lichens are symbiotic organisms and enrich with more lichen compounds. Lichens are widely used as traditional foods, ethanomedicines, and holy sacrifice fires. In the present study, Collection of native species of high altitude lichen Ramalina fastigiata was collected. Fe2O3 NPs were synthesized using R. fastigiata lichen extract and characterized. FTIR and GC–MS analysis was performed to identify the bioactive compounds helpful in the synthesis of Fe2O3 NPs as capping and reducing agents. The antioxidant and anticandida activities were evaluated by in-vitro method. Results showed that the synthesized Fe2O3 NPs had a spherical shape and free radical scavenging activity for 2,2-diphenyl-1-picrylhydrzyl (DPPH) radicals with an IC50 value of 6.5±0.4µg/ml , 4.1 ± 0.2µg/ml ABTS and 18.8±0.05µg/ml H2O2 . The antibacterial activity of the synthesized Fe2O3 NPs against the test organisms were susceptible in the following order C. albicans > C. parapsilosis > C. tropicalis> C. krusei> C. glabrata. Thus Fe2O3 NPs synthesized from high altitude lichen extract demonstrated that it has strong antioxidant and anticandida property with more importance in the field of nanomedicine.
Keywords	Lichen, Nanoparticles, Antioxidant
Field	Biology
Published In	Volume 7, Issue 2, March-April 2026
Published On	2026-04-16

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