Advanced International Journal for Research

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Analysis Data Obtained from Susceptibility Weighted Imaging for Evaluation of Hemorrhage, A Comparison with Gradient Echo Sequence in MRI-A Prospective Study

Author(s) Madan Kumar K, Namitha S, Dr. Mohammed Yaseen
Country India
Abstract Introduction: Magnetic Resonance Imaging (MRI) plays a vital role in detecting intracranial hemorrhage due to its superior soft tissue contrast and sensitivity. Among MRI sequences, Gradient Recalled Echo (GRE) has been widely used; however, Susceptibility Weighted Imaging (SWI) is a more advanced technique that enhances visualization of hemorrhagic lesions and microbleeds by exploiting magnetic susceptibility differences.
Objective: To evaluate the effectiveness of SWI in detecting intracranial hemorrhage and compare its diagnostic performance with GRE sequences using both manual and automated measurement methods.
Methodology: A hospital-based prospective study was conducted on 25 patients with clinically suspected brain hemorrhage. MRI scans were performed using a 1.5 Tesla system. GRE and SWI sequences were analyzed. Hemorrhage areas were measured manually and automatically using ImageJ software. Statistical analysis, including paired t-tests, was performed to compare sensitivity and measurement accuracy.
Results: SWI demonstrated higher detection rates compared to GRE. In trauma cases, detection was 100% (17/17) with SWI versus 92% (16/17) with GRE. For amyloid cases, SWI detected 100% (4/4), while GRE detected 0%. Mean hemorrhage area (manual) was lower in SWI (5.32 ± 4.09 sq.cm) than GRE (7.70 ± 5.64 sq.cm). Automated measurements showed improved sensitivity. Statistical analysis revealed significant differences (p = 0.00 for manual GRE vs SWI; p = 0.0006 for automated comparison).
Conclusion: SWI is significantly more sensitive and reliable than GRE in detecting intracranial hemorrhage and microbleeds. Automated measurement methods further enhance diagnostic accuracy, supporting SWI as a preferred imaging technique in neuroimaging.
Keywords MRI, Susceptibility Weighted Imaging, Gradient Echo, Intracranial Hemorrhage
Field Medical / Pharmacy
Published In Volume 7, Issue 2, March-April 2026
Published On 2026-04-22
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