A Brief Review of Patulin and Its Biological Significance

Author(s)	Dr. Kalaiselvi Vaithi, Ms. Elavarasi Rajavel, Dr. Vasanthabharathi Venkataraman
Country	India
Abstract	particularly Penicillium expansum, which commonly contaminates apples and other fruits during post-harvest storage. Traditionally, patulin has been regarded as a terrestrial mycotoxin associated with food spoilage and toxicological risks to human health. However, recent developments in marine mycology and natural product research have demonstrated that marine-derived fungi, including species of Penicillium, Aspergillus, and Byssochlamys isolated from marine sediments, seawater, and sponges, are also capable of producing patulin and structurally related analogs. These findings expand the ecological significance of patulin biosynthesis and suggest that marine ecosystems may serve as alternative reservoirs of bioactive mycotoxins. This review summarizes current knowledge on the occurrence, biosynthesis, and biological activities of patulin, with particular emphasis on its antimicrobial potential and its implications as a food contaminant and public health hazard.
Keywords	Patulin ,Mycotoxin, Antimicrobial activity, Food safety, Toxicity
Field	Biology
Published In	Volume 7, Issue 3, May-June 2026
Published On	2026-05-25
DOI	https://doi.org/10.63363/aijfr.2026.v07i03.5823

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