Advanced International Journal for Research

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Volume 7 Issue 3
May-June 2026

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Customising ecosystem to boost antimicrobial prophylaxis : Contemporary Review of UV-C rays and other modalities

Author(s) Dr. Kaustubh Bhardwaj, Dr. Riya Gupta, Dr. Swaraj Verma, Dr. Devashish Srivastava
Country India
Abstract Healthcare-associated infections (HAIs), and particularly those caused by multidrug-resistant organisms, remain a major source of morbidity, mortality and cost, and the contaminated hospital environment is an important reservoir driving their transmission. Because manual cleaning is inherently variable, there is growing interest in supplementary, “no-touch” and engineered strategies that shrink this reservoir. This review examines ultraviolet-C (UV-C) disinfection as the most extensively studied of these technologies, summarising how it works, how it is deployed and what the clinical and microbiological evidence shows: UV-C consistently reduces surface and air contamination, but its effect on actual infection rates is encouraging yet inconsistent and varies by pathogen. It then situates UV-C within a wider and rapidly evolving toolkit, spanning far-UV-C and upper-room ultraviolet systems, antimicrobial surfaces and coatings (including copper and silver), ventilation and filtration, wastewater-based environmental surveillance, and biological and ecological strategies such as bacteriophages, predatory bacteria, photodynamic therapy, engineered live bacteria and vector control. Traditional and complementary approaches, including Ayurvedic fumigation (Dhoopana) and camphor-containing essential oils, are also appraised. For every modality the available efficacy data are weighed against the relevant safety, ecological and ethical trade-offs, supporting the central conclusion that these interventions are best used as integrated adjuncts to, rather than replacements for, rigorous conventional cleaning.
Keywords healthcare-associated infections; multidrug-resistant organisms; UV-C disinfection; environmental disinfection; no-touch decontamination; infection prevention
Field Medical / Pharmacy
Published In Volume 7, Issue 3, May-June 2026
Published On 2026-06-19
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E-ISSN 3048-7641
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