Antibacterial Activity Of Silica With Copper Oxide Nanocomposite And Its Properties

Christy Sandra Fernando B; Nirmala Jothi N S

Antibacterial Activity Of Silica With Copper Oxide Nanocomposite And Its Properties

Author(s)	Ms. Christy Sandra Fernando B, Dr. Nirmala Jothi N S
Country	India
Abstract	Nanomaterials are efficient in their antibacterial characteristics. Metals and metal oxides have significant advantage especially copper oxide is preferred due to its enhanced anticancer and antimicrobial activity. The aim of this research article is to highlight the impact of “silica with copper oxide nanocomposite” for antibacterial properties. Silica is a non-toxic material obtained from its precursor, Tetraethyl orthosilicate (TEOS) and copper oxide was obtained from Copper Nitrate Trihydrate. Both the materials were synthesized by the “hydrothermal” method of nanotechnology. The prepared materials were combined in a solution phase to make it a nanocomposite. The material was tested for its structural properties using X-ray Diffraction (XRD), Field Emission Scanning Electron Microscopy (FESEM) with Energy Dispersive X-ray Analysis (EDAX), High-Resolution Transmission Electron Microscopy (HRTEM) with Selected Area Electron Diffraction (SAED). The particle size was found to be about 66 nm. The functional properties of the nanocomposite were analyzed by Fourier Transform Infrared Spectroscopy (FTIR) and Fourier Transform Raman (FT Raman) Spectroscopy techniques. The optical property of the sample was analyzed by Ultraviolet-Visible (UV) Spectroscopy technique. The band gap was found to be 1.4 eV from Tauc’s plot. The surface charge of the material was determined using Zeta potential, which is found to be negative. Finally, the material was tested against three gram-positive bacteria and seven gram-negative bacteria using disc diffusion method. The results revealed that Staphylococcus aureus (11mm), Streptococcus pyogenes (11mm), Enterococcus species (12mm), Escherichia coli (9mm), Pseudomonas aeruginosa (10mm), Proteus species (11mm), Salmonella species (10mm), Klebsiella pneumonia (9mm), Escherichia coli – ATCC 25922 (11mm), and Salmonella typhimurium – ATCC 14028 (11mm). The zone of inhibition was analyzed. The nano composite showed good antibacterial properties for tested bacteria. It can be used as antimicrobial agent.
Keywords	Nanotechnology, Silica, Copper oxide, Antibacterial property
Field	Physics
Published In	Volume 7, Issue 4, July-August 2026
Published On	2026-07-31

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Antibacterial Activity Of Silica With Copper Oxide Nanocomposite And Its Properties

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