First Order Derivative UV Spectroscopic Method Development and Validation of Vonoprazan Fumarate in Bulk and Tablet Dosage Form

Author(s)	Prof. Dr. Murugan S, Prof. Dr. Vetrichelvan T, Mr. Dhinesh Kumar R, Mr. Jagadesh M, Mr. Mohamed Nafees S, Mr. Naren Karthikeyan E, Mr. Vigneshwaran K M
Country	India
Abstract	The simple First Order Derivative UV Spectroscopic Method was developed for the determination of Vonoprazan in bulk and tablet dosage form. The method involved in first order derivative. In first order the wavelength selected was 216 nm. The method was found to be linear between the range of 20-100 μg/ml for Vonoprazan in Distilled Water. The First-order derivative method was successfully applied for the assay of Vonoprazan in bulk and tablet dosage form and validated as per ICH guidelines
Keywords	Vonoprazan, First order, UV Method, Distilled Water
Field	Medical / Pharmacy
Published In	Volume 7, Issue 4, July-August 2026
Published On	2026-08-24
DOI	https://doi.org/10.63363/aijfr.2026.v07i04.7453

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