Advanced International Journal for Research

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Volume 7 Issue 5
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How Placebo can work as a treatment for Depression

Author(s) Ms. Yunseon Sunny Lee
Country Malaysia
Abstract Placebo is like a shadow but unlike a shadow simultaneously. Though biologically no reason to change one’s body is given, placebo will gradually ease the pain, as if the medicine is given to the patient. Placebo has been a popular option in major hospitals due to its speciality of absence of side effects that can be produced by the medicines or surgeries. Furthermore, placebo can be utilised especially well to cure mental disorders compared to other pathogenic diseases since mental disorders are rather subjective and don’t necessarily require treatments for infection. To apply this idea to real life, I reflected on how the belief of listening to the scientifically-proven mood-boosting music could actually lead to an improvement in the students’ emotions, which aligns with what I sought out to investigate but not directly. I randomly selected 10 students, which is a relatively small sample size, in my school, in the same age group between 16 to 18. To assess their basic emotional status, I conducted the Oxford Happiness Questionnaire (OHQ) before and after the experiment to compare any change from listening to music, and Patient Health Questionnaire-9, before the experiment to measure the severity of student’s depression using a Google Form; both are self-assessed report. Half of the sample listened to the music that has been scientifically shown the correlation between listening to the music and improvement in emotion swings from Brain.fm, while the other half listened to the placebo, a frequency-based music, which isn’t scientifically proven to impact one’s emotions. The results showed that the higher the severity of depression, the greater improvement in OHQ showed after the experiment for both placebo and the other group. Furthermore, placebo and the other group that listened to the real mood-improving music showed similar results in the change of OHQ after the experiment.
Keywords placebo, depression
Field Medical / Pharmacy
Published In Volume 7, Issue 5, September-October 2026
Published On 2026-09-07
DOI https://doi.org/10.63363/aijfr.2026.v07i05.7645
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