Advanced International Journal for Research

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A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 7, Issue 5 (September-October 2026) Submit your research before last 3 days of October to publish your research paper in the issue of September-October.

Dermatophytosis: An Updated Review Of Epidemiology, Pathogenesis, Diagnosis, Antifungal Resistance And Treatment

Author(s) Ms. Sivasankari M, Dr. Senthil Rajan D, Ms. Haripriya R, Ms. Dharshini M, Ms. Jainab C, Ms. Anuvidhya P, Ms. Archana M
Country India
Abstract Dermatophytosis, commonly known as ringworm or tinea infection, is one of the most prevalent superficial fungal infections affecting keratinized tissues, including the skin, hair, and nails. It is primarily caused by dermatophytes belonging to the genera Trichophyton, Microsporum, and Epidermophyton. The infection can occur in different anatomical forms, including tinea corporis, tinea capitis, tinea pedis, tinea cruris, tinea faciei, tinea manuum, tinea barbae, and tinea unguium. Warm and humid environmental conditions, excessive sweating, close contact with infected individuals or animals, contaminated fomites, poor hygiene, and certain host-related factors contribute to the transmission and persistence of dermatophytosis. This review summarizes the current understanding of the aetiology, classification, pathogenesis, epidemiology, clinical manifestations, and diagnostic approaches used for dermatophyte infections. Conventional diagnostic methods such as direct microscopic examination using potassium hydroxide, fungal culture, dermoscopy, Wood's lamp examination, and skin biopsy, along with molecular diagnostic techniques, are discussed. Particular attention is given to the increasing emergence of antifungal-resistant dermatophytes, especially Trichophyton indotineae, and the molecular mechanisms associated with resistance to terbinafine and azole antifungals. Current pharmacological and non-pharmacological treatment approaches, including topical and systemic antifungal therapy, are also reviewed. The potential role and limitations of combination antifungal therapy and the use of non-antifungal agents as adjunctive treatments are highlighted. Overall, early and accurate diagnosis, appropriate antifungal selection, treatment adherence, and preventive measures are essential for improving therapeutic outcomes and reducing recurrence and transmission. Continued research into antifungal resistance, novel therapeutic strategies, and improved susceptibility testing methods is required to address the evolving challenges associated with dermatophytosis.
Keywords Dermatophytosis, Ringworm, Trichophyto,; Microsporum, Epidermophyton, Antifungal resistance, Trichophyton indotinea, Terbinafine, Azoles, Diagnosis, Treatment.
Field Medical / Pharmacy
Published In Volume 7, Issue 5, September-October 2026
Published On 2026-09-10

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