Advanced International Journal for Research

E-ISSN: 3048-7641     Impact Factor: 9.11

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 7, Issue 1 (January-February 2026) Submit your research before last 3 days of February to publish your research paper in the issue of January-February.

Advancement and Interpretation Embodied Herbal Vitamin ‘C’ And Milk Thistle Nutraceutical Gummies

Author(s) Ms. REKHA KANDUKURI, Mr. YADAV DEVENDRA N, Mr. AMARNATHREDDY A, Ms. LAVANYA N
Country India
Abstract The present study focuses on the formulation and evaluation of nutraceutical gummies incorporating Silybum marianum (Milk Thistle) seed extract and herbal Vitamin C derived from guava fruit powder, designed to deliver antioxidant and hepatoprotective benefits in a palatable oral dosage form. Conventional dosage forms such as tablets and capsules often suffer from swallowing difficulties and reduced compliance; hence, a gelatin-based gummy matrix was developed as a patient-friendly alternative combining efficacy with sensory appeal. Four formulations (F1–F4) were prepared by varying the concentrations of S. marianum extract and water content. The optimized formulation utilized gelatin, sucrose, glucose, citric acid, and guava powder, which provided both flavor and Vitamin C enrichment. Evaluations included morphological characteristics, pH, moisture content, texture, microbial stability, and storage stability. Among all, formulation F3 demonstrated superior physical characteristics with optimal pH (4.0), desirable softness, non-stickiness, and absence of microbial contamination during a 20day observation period. The combination of silymarin and herbal Vitamin C exhibited synergistic antioxidant potential, contributing to enhanced detoxification and skin health benefits. Overall, the formulation of Milk Thistle–Vitamin C gummies proved stable, pleasant, and safe, illustrating the feasibility of developing an effective antioxidant nutraceutical in gummy form. Future studies will emphasize quantifying antioxidant activity, bioavailability, and large-scale manufacturing feasibility.
Key words: MILKTHISTLE POWDER,GUAVA FRESH FRUIT,GUAVA FRUIT POWDER BY FREEZE DRIED,GELATIN,ASCORBIC ACID,SUCROSE,PURIFIED WATER .
Keywords MILKTHISTLE POWDER,GUAVA FRESH FRUIT,GUAVA FRUIT POWDER BY FREEZE DRIED,GELATIN,ASCORBIC ACID,SUCROSE,PURIFIED WATER .
Field Chemistry > Pharmacy
Published In Volume 7, Issue 1, January-February 2026
Published On 2026-01-24

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