Green Synthesis of Cobalt Oxide Nanoparticles Derived from Calotropis procera Leaves and their Comprehensive Evaluation of Antibacterial Properties

Author(s)	Riya Devi, Anshul Chaubey, Nirbhik Karan, Dev Sharan Chaturvedi
Country	India
Abstract	The antibacterial activity of CoO nanoparticles was evaluated against two bacterial strains, Staphylococcus aureus and Pseudomonas aeruginosa, at concentrations of 10 µg/mL, 25 µg/mL, and 50 µg/mL. The results demonstrated a clear dose-dependent increase in antibacterial activity, with the highest concentration showing the largest zones of inhibition. The 50 µg/mL concentration of CoO nanoparticles exhibited antibacterial activity comparable to or even superior to ciprofloxacin (30 µg/mL), particularly against Pseudomonas aeruginosa. These results underscore the strong antimicrobial potential of CoO nanoparticles, making them promising candidates for use in the development of new antimicrobial agents.
Keywords	Calotropis procera, Comprehensive, Cobalt Oxide Nanoparticles, Green Synthesis Mycobacterium tuberculosis, Plasmodium species, morbidity, electrophoresis, Particle Size Analysis, Dynamic Light Scattering
Field	Medical / Pharmacy
Published In	Volume 7, Issue 1, January-February 2026
Published On	2026-01-12
DOI	https://doi.org/10.63363/aijfr.2026.v07i01.2978
Short DOI	https://doi.org/hbk6zt

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