Role of Nanoparticles in Enhancing the Sensitivity and Selectivity of Forensic Toxicological Analysis

Author(s)	Ms. Fathima Jinsha PB, Mr. Indrajith VS, Ms. Sakshi Manhas
Country	India
Abstract	This review highlights the pivotal role of nanoparticles in enhancing forensic toxicology by overcoming the sensitivity and selectivity limitations of conventional methods for detecting trace toxicants in complex biological matrices. Leveraging unique properties such as surface plasmon resonance, high surface area, and catalytic activity, nanoparticles amplify signals and improve detection when integrated with analytical techniques like mass spectrometry, chromatography, and electrochemical sensors. Practical applications demonstrate superior performance in identifying pharmaceuticals, illicit drugs, pesticides, and pollutants. However, challenges in nanoparticle synthesis, stability, and regulatory approval must be resolved to enable their routine adoption, which holds significant promise for advancing forensic analytical platforms.
Keywords	Keywords - Forensic toxicology, Nanoparticles, Sensitivity, Selectivity, Analytical techniques
Published In	Volume 7, Issue 1, January-February 2026
Published On	2026-01-29
DOI	https://doi.org/10.63363/aijfr.2026.v07i01.3147
Short DOI	https://doi.org/hbmz2f

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